Tribulation or persecution comes because of the word
20 But he that received the seed into stony places, the same is he that heareth the word, and anon with joy receiveth it;
21 Yet hath he not root in himself, but dureth for a while: for when tribulation or persecution (θλίψεως ἢ διωγμοῦ διὰ) ariseth because of the word, by and by he is offended.
Great persecution against the church which was at Jerusalem
1 And Saul was consenting unto his death. And at that time there was a great persecution (διωγμὸς μέγας) against the church which was at Jerusalem; and they were all scattered abroad throughout the regions of Judaea and Samaria, except the apostles.